Clearance of cell debris is the key process in healthy aging
Diet, exercise and genetics determine your rate of clearance
Cell debris is cleared by the body exploiting two key mechanisms, phagocytosis and autophagy
E3Bio are developing a first in class molecule to stimulate clearance allowing effective regeneration
Stimulators of Phagocytosis
Stimulators of Autophagy
Debris formed into an 'autophagosome'
Macromolecules are broken down in the autophagosome Principal mechanism for clearing misfolded proteins and insoluble protein aggregates